(NBC)–U.S. swimmers Michael Phelps, Ryan Lochte, Missy Franklin and Nathen Adrian are back in the pool on Wednesday.
The preliminaries began Wednesday afternoon, where Lochte kicked off his first individual swim of the Rio Games by topping the competition.
He clocked in at 1:57.38 in the 200-meter individual medley, one of his best events at the Olympics. He won silver in 2004 and 2012 and bronze in 2008.
Phelps, who won his 20th and 21st gold medals on Tuesday, also won his heat with a time of 1:58.41. He heads into Wednesday evening’s IM semifinal against his teammate with the third best time of the group of 16.
Phelps and Lochte led the U.S. men’s relay team to gold in the 4×200 freestyle.
Katie Ledecky, meanwhile, could be looking for more gold in the women’s 4X200 freestyle along with Missy Franklin and other teammates. The preliminary swim Wednesday afternoon featured Allison Schmitt, Franklin, Melanie Margalis and Cierra Runge. It will be followed by the final in the evening.
Two Americans have a shot at a medal in the women’s 200-meter butterfly Wednesday night: Cammile Adams and Hali Flickinger, who advanced into the finals in sixth place.
Nathan Adrian will also try to defend his 100-meter Olympic title in the freestyle final. He’ll be up against Australia’s Cameron McEvoy, who swam half a second faster than Adrian has ever gone during the trials in Australia.
No American man has won a gold medal in the 200-meter breaststroke since Mike Barrowman finished first in 1992. But Josh Prenot and Kevin Cordes could end that in Wednesday’s medal event.
Rounding out the heats Wednesday afternoon were the women’s 100-meter freestyle, the men’s 200-meter backstroke and women’s 200-meter breaststroke.
American Simone Manuel won her heat in the 100-meter freestyle and Abbey Weitzeil also made the semifinals set for Wednesday evening.
Ryan Murphy and teammate Jacob Pebley advanced to the 200-meters backstroke semifinals.